Frequent question: Can xylitol cause kidney failure in dogs?

Abstract : Two dogs were referred due to vomiting, depression and anorexia after ingestion of xylitol gum. Both dogs were presented with hepatic failure and one dog had concurrent renal failure. Aggressive supportive treatment was performed, but these dogs died.

How long does it take for xylitol to affect a dog?

After ingesting xylitol, dogs typically develop symptoms within 30 minutes (although they can be very rapid or take up to 12 hours). Signs of dog xylitol poisoning can include: vomiting. lethargy.

Can a dog recover from xylitol poisoning?

What is the prognosis for recovery from xylitol poisoning? The prognosis is good for dogs that are treated before clinical signs develop, or for dogs that develop uncomplicated hypoglycemia that is quickly reversed. If liver failure develops, the prognosis is generally guarded and patients may need prolonged treatment.

What are the symptoms of xylitol poisoning in dogs?

Symptoms of xylitol poisoning in dogs include vomiting, followed by symptoms associated with the sudden lowering of your dog’s blood sugar, such as decreased activity, weakness, staggering, incoordination, collapse and seizures.

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How many dogs have died from xylitol?

There have been no reported deaths associated with those dogs that developed uncomplicated hypoglycemia. In the less than 1/1000 dogs who develop acute liver failure, the mortality rate is 70-80%. Hepatic failure, with destruction of the liver tissue, can occur within 9-72 hrs of ingestion at xylitol doses >1.0 g/kg.

Does xylitol have any side effects?

Xylitol is generally well tolerated, but some people experience digestive side effects when they consume too much. The sugar alcohols can pull water into your intestine or get fermented by gut bacteria ( 28 ). This can lead to gas, bloating and diarrhea. However, your body seems to adjust very well to xylitol.

How bad is gum for dogs?

As few as one or two sticks of some gums containing xylitol can be toxic to dogs of all sizes. Cummings Veterinary Medical Center says the ingredient can cause a dangerous drop in blood sugar. The most serious cases can result in liver failure.

Does xylitol cause liver damage in dogs?

Xylitol consumption is considered harmless to people but is known to cause life-threatening toxicoses in dogs. Dogs that ingest doses of >0.1 g/kg of xylitol are at risk for developing hypoglycemia, while dogs that ingest >0.5 g/kg may develop acute liver failure.

Does xylitol cause permanent liver damage in dogs?

In most cases, the liver enzyme elevations are mild, and dogs recover completely with a little help from medication that protects the liver. However, very large doses of xylitol in dogs can lead to liver failure, which is a much more serious and possibly fatal condition.

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What causes acute liver failure in dogs?

Acute liver failure is most often caused by infectious agents or toxins, poor flow of fluids into the liver and surrounding tissues (perfusion), hypoxia (inability to breathe), drugs or chemicals that are destructive to the liver (hepatotoxic), and excess exposure to heat.

What happens if a dog eats Trident gum?

Xylitol causes a rapid and severe increase in insulin in the blood of dogs. This in turn causes a severe drop in blood sugar. Xylitol can also be toxic to the liver.

What if a dog eats xylitol gum?

If you suspect that your dog may have consumed sugar-free gum or any other product containing xylitol, immediately call your vet or the Pet Poison Helpline (800-213-6680). Do not induce vomiting or give anything orally to your dog unless specifically directed to do so by your veterinarian.

Does Trident have xylitol?

Trident gum contains the sugar alcohol xylitol, which is known as a “tooth-friendly” sugar. Use of the chemical has been subject to controversy, as it is highly toxic to dogs.

Which peanut butter has xylitol?

There are currently five peanut butter brands that use xylitol: Go Nuts Co., Krush Nutrition, Nuts ‘N More, P28 Foods, and Protein Plus PB.